Texas A&M University System (TAMUS) and Greffex, Inc. sign agreement to collaborate on advanced process and manufacturing development.

May 15, 2017

Greffex, Inc. and the Texas A&M University System (TAMUS) are excited to announce a collaboration on advanced process and manufacturing development. This agreement will advance the research and development of Greffex vaccines and assist the Health Science Center’s Center for Innovation in Advanced Development and Manufacturing (CIADM) at TAMUS to establish a robust, efficient pipeline of countermeasures to public health emergencies both in the US and worldwide.

From the press release:

“As we prepare for the next phase of research and development, we needed a creative, innovative “university-based” partner to assist us in our long-range development plans,” said John R. Price, President and CEO of Greffex, “and in Texas A&M Health Science Center’s Center for Innovation in Advanced Development and Manufacturing (CIADM), we found the creative, forward-thinking researchers who can leverage the resources of the entire university system.”

Read the full Press Release here>>

NIAID TESTS GREFFEX’S MERS-CoV VACCINE

September 4, 2014

In the summer of 2014, Greffex was asked by the National Institute of Allergy and Infectious Diseases (NIAID) for a sample of its vaccine for MERS-CoV so that it could run tests to evaluate the production of neutralizing antibodies.

On a very tight schedule (less than two months) Greffex produced, purified, and vaccinated animals with the GreMERSfi. Mice were immunized in a prime/boost schedule with a small dose (approx. 3×108 genome equivalents).  A standard micro-neutralization assay was used to quantify the humoral immune responses. All of the animals raised significant levels of neutralizing antibodies. 75% of the animals presented with very high antibody titers in the range of 640 to more than 2,560 (the test limit).  In light of these results, the NIAID has invited Greffex to request further trials under its sponsorship.